Precipio Inc HS-FF-KIT - Molecular Reagent… | USA MedPremium
Molecular Reagent HemeScreen® KIT For Research Use Only For HRM-enabled RT-PCR Machine / AML Panel 100 Tests
USAMP#27340208SKU: HS-FF-KITHemeScreen®
Product Spotlight
Precipio’s HemeScreen® offerings are Research Use Only (RUO) assays thatscreen for clinically actionable somatic mutations in targets of interest related to myeloproliferative disorders and haematological cancers
The reagents are designed to be used in a clinical diagnostic laboratory by suitably trained personnel testing DNA extracted from whole blood or bone marrow using a PCR-based method and High Resolution Melt (HRM) Analysis
High Resolution Melting (HRM) is a screening technique, which allows the user to determine if the PCR fragment contains a variant or not based upon the dissociation of double-stranded DNA in the presence of an intercalating dye as the temperature increases
KIT mutation expression is found in approximately 80% of cases
RUNX1 cytogenetic mutation is commonly associated with KIT mutation - treatments include chemotherapy as well as inhibitors such as Dasatinib and Radotinib
Free-Flow Reagent
Each HemeScreen® reagent sets contains enough reactions for 100 samples in duplicate and includes enough Mutant control for 5 reactions
Reagent sets should be stored in the dark between -18 °C and -25 °C in a constant temperature freezer until use
