Sodium Butyrate is the sodium salt of butyric acid, a short chain fatty acid that inhibits histone deacetylases (HDACs), leading to hyperacetylation of histones - this causes changes in chromatin structure and gene expression, resulting in many biological effects
Epigenetic modifier; Inhibits histone deacetylase
Promotes reprogramming of human somatic cells to induced pluripotent stem (iPS) cells using only a single factor, OCT4 (Zhu et al.)
upports self-renewal of mouse and human embryonic stem (ES) cells, in the absence of exogenously added growth factors (Ware et al.)
